The association of eosinophilic polyarteritis, libman-sacks endocarditis, and asthma with diffuse collagen disease.

In the last decade a considerable number of papers have been written describing fatal illnesses in which the salient clinical features were asthma, eosinophilia, and heart failure. Weir (1939), Harkavy (1941), Chafee, Ross, and Gunn (1942), Miller and Daley (1946), Bergstrand (1946), Smith (1948), and Lennox (1948) have all reported such cases, the clinical course of which differed little from the comparatively common asthma ending in heart failure or occasionally status asthmaticus. The post-mortem findings, however, showed lesions which linked those cases with the socalled collagen diseases or allergic syndromes. In view of the great interest in collagen diseases at present the following case seems to be worthy of record.